Development of a certified reference material for anti-β2-glycoprotein I IgG – commutability studies
نویسندگان
چکیده
منابع مشابه
Optimization of Unnicked β2-Glycoprotein I and High Avidity Anti-β2-Glycoprotein I Antibodies Isolation
Patient biological material for isolation of β2-glycoprotein I (β2GPI) and high avidity IgG anti-β2-glycoprotein I antibodies (HAv anti-β2GPI) dictates its full utilization. The aim of our study was to evaluate/improve procedures for isolation of unnicked β2GPI and HAv aβ2GPI to gain unmodified proteins in higher yields/purity. Isolation of β2GPI from plasma was a stepwise procedure combining n...
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BACKGROUND To address the continuing need for the standardization of clinical human cardiac troponin I (cTnI) assays, NIST, with the assistance of the AACC/IFCC Cardiac Troponin I Standardization Committee, has developed a new certified reference material, Standard Reference Material (SRM) 2921: Human Cardiac Troponin Complex. METHODS The concentration of cTnI in SRM 2921 was determined throu...
متن کاملMeasuring IgA Anti-β2-Glycoprotein I and IgG/IgA Anti-Domain I Antibodies Adds Value to Current Serological Assays for the Antiphospholipid Syndrome
INTRODUCTION Currently available clinical assays to detect antiphospholipid antibodies (aPL) test for IgG and IgM antibodies to cardiolipin (aCL) and β2-glycoprotein I (aβ2GPI). It has been suggested that testing for IgA aPL and for antibodies to Domain I (DI), which carries the key antigenic epitopes of β2GPI, could add value to these current tests. We performed an observational, multicenter c...
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An infant formula certified reference material (CRM) for the analysis of vitamins was developed. Vitamin A, folic acid, niacin, were certified and their stability has been monitored by using isotope dilution-liquid chromatography/mass spectrometric (ID-LC/MS) methods developed in our laboratories as primary methods for the corresponding analytes. Certification of α-, δ-, and γtocopherols in the...
متن کاملDevelopment of a Certified Reference Material for Nicotinamide in Infant Formula
Nicotinamide, one kind of Vitamin B, plays an important role for humans. To ensure quality control of nicotinamide in infant formula, a Certified Reference Material for nicotinamide in infant formula is being prepared in China for the first time. Studying on the procedure of sample preparation and HPLC analysis with different detectors like UV and MS, HPLC-UV and HPLC-IDMS are selected as the v...
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ژورنال
عنوان ژورنال: Clinical Chemistry and Laboratory Medicine (CCLM)
سال: 2020
ISSN: 1437-4331,1434-6621
DOI: 10.1515/cclm-2020-0995